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80902-29-0

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1 Results for "80902-29-0" in MCE Product Catalog:

Cat. No.: HY-137618B
CAS No.: 80902-29-0
Target:  

HIV

Research Areas:  

Others

Rp-dGTPαS is the nucleotide substrate of SAMHD1 and is one of the enantiomers of the dNTPαS nucleotide. SAMHD1 is an essential regulator of cellular dNTPs that limits virus (HIV-1, etc.) replication in the CD4+ myeloid lineage and resting T cells. The SAMHD1 tetrameric complex catalyzes the hydrolysis of Rp-dGTPαS into 2'-deoxynucleosides and triphosphates .
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