1 Result for "

8305C cells

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "8305C cells" in MCE Product Catalog:

Cat. No.: HY-164413
CAS No.: 1312024-59-1
Target:  

VEGFR EGFR RET Apoptosis

Research Areas:  

Cancer

CLM3, a pyrazolopyrimidine derivative, is a multiple tyrosine kinase inhibitor. CLM3 shows antiproliferative and proapoptotic activity on endothelial and cancer cells, synergistically enhanced by SN38 (HY-13704). These effects are mainly due to its inhibition of phosphorylation of VEGFR-2, EGFR and RET tyrosine kinases and their related signaling pathways .
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