1 Result for "

A1048400

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "A1048400" in MCE Product Catalog:

Cat. No.: HY-120484
CAS No.: 1219624-62-0
Target:  

Calcium Channel

Research Areas:  

Neurological Disease

A-1048400 is an orally active and selective calcium channel inhibitor with an IC50 value of 1.4 μM for N-type channels, 1.2 μM for T-type channel. A-1048400 inhibits neurotransmitter release and reduces membrane hyperexcitability, exerting potent analgesic activity. A-1048400 is promising for research of neuropathic pain (e.g., pain induced by spinal nerve ligation and chronic constriction injury) .
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