1 Result for "

ALK5-IN-82

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ALK5-IN-82" in MCE Product Catalog:

Cat. No.: HY-162902
CAS No.: 3001361-04-9
Target:  

TGF-β Receptor

Research Areas:  

Cardiovascular Disease

ALK5-IN-82 is a potent and selective inhibitor against activin receptor-like kinase 5 (ALK5) with an IC50 value of 9.1 nM. ALK5-IN-82 inhibits the protein expression of α-smooth muscle actin (α-SMA), collagen I and tissue inhibitor of metalloproteinase 1 (TIMP-1)/matrix metalloproteinase 13 (MMP-13) in transforming growth factor-β-induced human umbilical vein endothelial cells. ALK5-IN-82 is promising for research of cardiac fibrosis .
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