1 Result for "

ATRi

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ATRi" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-139609
CAS No.: 2417489-10-0
Purity:  99.75%
Synonyms: RP-3500; ATR inhibitor 4
Target:  

ATM/ATR mTOR

Research Areas:  

Cancer

Camonsertib (RP-3500) is an orally active, selective ATR kinase inhibitor (ATRi) with an IC50 of 1.00 nM in biochemical assays. Camonsertib shows 30-fold selectivity for ATR over mTOR (IC50=120 nM) and >2,000-fold selectivity over ATM, DNA-PK, and PI3Kα kinases. Camonsertib has potent antitumor activity .
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