1 Result for "

AVE0118

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "AVE0118" in MCE Product Catalog:

Cat. No.: HY-118387
CAS No.: 498577-53-0
Target:  

Potassium Channel

Research Areas:  

Cardiovascular Disease

AVE-0118 is a Kv1.5 potassium channel blocker and antiarrhythmic agent. AVE-0118 blocks neuronal Kv1.5 potassium channels, thereby enhancing the release of norepinephrine. AVE-0118 enhances field stimulation-induced neurogenic contraction, an effect sensitive to α1-adrenergic receptor blockade. AVE-0118 terminates persistent atrial fibrillation in some dogs. AVE-0118 is applicable to research related to atrial fibrillation and persistent atrial fibrillation .
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