1 Result for "

AZ 3976

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "AZ 3976" in MCE Product Catalog:

Cat. No.: HY-117724
CAS No.: 1418747-15-5
Purity:  98.03%
Target:  

PAI-1

Research Areas:  

Cardiovascular Disease

AZ3976 is a potent plasminogen activator inhibitor type 1 (PAI-1) inhibitor with an IC50 value of 26 μM in an enzymatic chromogenic assay. AZ3976 is active with an IC50 of 16 μM in a plasma clot lysis assayAZ3976 does not bind to active PAI-1 but bound reversibly to latent PAI-1. AZ3976 inhibits PAI-1 by enhancing the latency transition of active PAI-1. AZ3976 displays profibrinolytic activities in a human plasma clot lysis assay .
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