1 Result for "

Ac-MRGDH-NH2

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "Ac-MRGDH-NH2" in MCE Product Catalog:

Ac-MRGDH-NH2
Ac-MRGDH-NH2
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Cat. No.: HY-P10667
Target:  

Integrin

Research Areas:  

Cancer

Ac-MRGDH-NH2 is a pentapeptide containing the RGD sequence. Ac-MRGDH-NH2 can be used to synthesize the diastereoisomeric prodrugs Λ- and Δ-[Ru(Ph2phen)2(κS,κN-(Ac-MRGDH-NH2))]Cl2. In these prodrugs, Ac-MRGDH-NH2 serves as a photolabile protecting group for the cytotoxic bis-aqua ruthenium warhead [Ru(Ph2phen)2(OH2)2]2+, and Ac-MRGDH-NH2 possesses integrin targeting ability and photosubstitution properties. Therefore, Ac-MRGDH-NH2 can be utilized in research on tumor-targeted photodynamic activation chemotherapy (PACT) .
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