1 Result for "

Acsl5 knockout mice

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Acsl5 knockout mice" in MCE Product Catalog:

Cat. No.: HY-186096
Research Areas:  

Metabolic Disease

LP-856866 is an orally active ACSL5 inhibitor, with IC50 values of 8 nM and 4 nM against mouse and human ACSL5, respectively, and IC50 values of 6 nM and 17 nM against mouse and human ACSL1, respectively. LP-856866 induces delayed gastric emptying, promotes GLP-1 release, reduces food intake, decreases body weight and body fat mass, preserves lean body mass, improves glucose homeostasis, enhances insulin sensitivity, reduces hepatic lipid accumulation, and lowers serum triglyceride and total cholesterol levels. LP-856866 is applicable to research on diet-induced obesity .
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