1 Result for "

Akt RIMTAC1

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Akt RIMTAC1" in MCE Product Catalog:

Cat. No.: HY-187500
Target:  

Akt PROTACs RIP kinase

Domaines de recherche:  

Others

Akt RIMTAC-1 is a Akt RIMTAC degrader (a PROTAC-like agent) with a DC50 of 3.52 μM. Akt RIMTAC-1 forms a ternary complex with AKT and RIPK1, and recruits the VHL E3 ligase complex to mediate ubiquitination and proteasomal degradation. Akt RIMTAC-1 does not alter AKT1 mRNA levels (pink: AKT ligand-5 (HY-187501); blue: RIPK1-ligand-4 (HY-187391); black: Linker (HY-23166)) .
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