1 Result for "

Anticancer agent-324

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Anticancer agent-324" in MCE Product Catalog:

Cat. No.: HY-P11828
Target:  

Survivin Caspase Apoptosis

Research Areas:  

Cancer

Anticancer agent 324 is a Survivin inhibitor. Anticancer agent 324 competitively binds to Survivin’s linker region and triggers proteasomal IAP degradation. Anticancer agent 324 blocks Borealin binding and chromosomal passenger complex formation, and inhibits Survivin-CRM1 nuclear-cytoplasmic transport. Anticancer agent 324 activates extrinsic (caspase-8) and intrinsic (caspase-9) apoptotic pathways, activates executioner caspases-3 and caspases-7, and arrests cell cycle. Anticancer agent 324 can be used for the research of breast cancer .
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