2 Results for "

Antiproliferative agent37

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Antiproliferative agent37" in MCE Product Catalog:

Cat. No.: HY-156183
CAS No.: 2989275-31-0
Purity:  98.29%
Target:  

MDM-2/p53 ERK

Research Areas:  

Cancer

Antiproliferative agent-37 (compound 10J) shows anti-proliferative effect by arresting the cells at the G2/M phase of the cell cycle .
loading...
    loading...
Cat. No.: HY-145289
CAS No.: 3032101-64-4
Target:  

Apoptosis

Research Areas:  

Cancer

Antitumor agent-37 possesses potent anti-proliferative and anti-metastasis activities. Antitumor agent-37 induces serious DNA damage and further leads to high expression of γ-H2AX and p53. Antitumor agent-37 promotes apoptosis of tumor cells through mitochondrial apoptotic pathway Bcl-2/Bax/caspase3. Antitumor agent-37 significantly improves immune response through restraining the expression of PD-L1 to increase CD3+ and CD8+ T infiltrating cells in tumor tissues .
loading...
    loading...