1 Result for "

BDTX189

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "BDTX189" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-136789
CAS No.: 2414572-47-5
Purity:  99.69%
Synonyms: BDTX-189
Target:  

EGFR

Research Areas:  

Cancer

Tuxobertinib (BDTX-189) is a potent, orally active and selective inhibitor of allosteric EGFR and HER2 oncogenic mutations, including EGFR/HER2 exon 20 insertion mutants. Tuxobertinib shows KDs of 0.2, 0.76, 13 and 1.2 nM for EGFR, HER2, BLK and RIPK2, reapectively. Anticancer activity .
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