1 Result for "

BG11

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "BG11" in MCE Product Catalog:

Cat. No.: HY-172092
CAS No.: 3065877-52-0
Target:  

Apoptosis Ferroptosis

Research Areas:  

Cancer

BG11 induces the accumulation of Fe 2+ and intracellular lipid peroxides, induces ferroptosis. BG11 regulates the expression of Bax and Bcl-2 proteins, and induces apoptosis in MDA-MB-231 cell. BG11 arrests the cell cycle at G0/G1 and S phase, inhibits the proliferation of TNBC cancer cell (IC50 for MDA-MB-231 and BT549 is 0.49 μM and 0.52 μM), and inhibits the cell migration and invasion. BG11 exhibits antitumor efficacy in mouse models .
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