1 Result for "

BI1622

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "BI1622" in MCE Product Catalog:

Cat. No.: HY-150023
CAS No.: 2681392-19-6
Purity:  98.97%
Target:  

EGFR Itk PI4K Btk CDK Raf JAK

Research Areas:  

Cancer

BI-1622 is an orally active, potent and highly selective HER2 (ERBB2) inhibitor, with an IC50 of 7 nM. BI-1622 shows greater than 25-fold selectivity over EGFR. BI-1622 shows high antitumor efficacy in vivo in xenograft mouse tumor models with engineered H2170 and PC9 cells and had a favorable agent metabolism and pharmacokinetics profile .
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