1 Result for "

BMS986251

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "BMS986251" in MCE Product Catalog:

Cat. No.: HY-136527
CAS No.: 2460133-35-9
Target:  

ROR Interleukin Related

Research Areas:  

Inflammation/Immunology

BMS-986251 is an orally active and selective RORγt inverse agonist with an EC50 of 12 nM for RORγt GAL4. BMS-986251 inhibits IL-17 with an EC50 of 24 nM in human whole blood assay. BMS-986251 demonstrates robust efficacy in mouse acanthosis and Imiquimod-induced (HY-B0180) models (preclinical models of psoriasis) .
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