2 Results for "

Balinatunfib

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Balinatunfib" in MCE Product Catalog:

Cat. No.: HY-160412
CAS No.: 2248726-53-4
Synonyms: SAR-441566; TNFα activity modulator 3
Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

Balinatunfib (SAR-441566) is an orally active inhibitor of TNFR1 signaling. By binding to the central pocket of the soluble TNFα (sTNFα) trimer, Balinatunfib stabilizes an asymmetric conformation, blocking its binding to TNFR1 (without affecting TNFR2) and thus inhibiting downstream pathways. Balinatunfib has anti-inflammatory activity, and can be used in the study of autoimmune diseases .
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Cat. No.: HY-P10680
Target:  

Liposome

Research Areas:  

Others

TFE-IDAtp1-LinA is a highly potent amphiphilic carrier, containing a trifluoroethyl-iminodiacetic acid analog of Stp. TFE-IDAtp1-LinA, formed nanoparticles with Cas9 RNP/ssDNA, achieved enhanced green fluorescent protein knockouts with an ED50 of 0.38 nM Cas9/sgRNA ribonucleoproteins (RNP) .
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