2 Results for "

Bis VIII

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Bis VIII" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-129624A
CAS No.: 138516-31-1
Purity:  99.68%
Synonyms: Ro 31-7549 acetate; Bis VIII acetate
Target:  

PKC Apoptosis

Research Areas:  

Inflammation/Immunology Cancer

Bisindolylmaleimide VIII acetate (Ro 31-7549 acetate) is a potent and selective protein kinase C (PKC) inhibitor with an IC50 of 158 nM for rat brain PKC. Bisindolylmaleimide VIII acetate has IC50s of 53, 195, 163, 213, and 175 nM for PKC-α, PKC-βI, PKC-βII, PKC-γ, PKC-ε, respectively . Bisindolylmaleimide VIII acetate facilitates Fas-mediated apoptosis and inhibits T cell-mediated autoimmune diseases .
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Cat. No.: HY-129624
CAS No.: 125313-65-7
Synonyms: Ro 31-7549; Bis VIII
Target:  

PKC Apoptosis

Research Areas:  

Inflammation/Immunology Cancer

Bisindolylmaleimide VIII (Ro 31-7549) is a potent and selective protein kinase C (PKC) inhibitor with an IC50 of 158 nM for rat brain PKC. Bisindolylmaleimide VIII has IC50s of 53, 195, 163, 213, and 175 nM for PKC-α, PKC-βI, PKC-βII, PKC-γ, PKC-ε, respectively . Bisindolylmaleimide VIII facilitates Fas-mediated apoptosis and inhibits T cell-mediated autoimmune diseases .
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