1 Result for "

CE-355621

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "CE-355621" in MCE Product Catalog:

Cat. No.: HY-P991565

Target:  

c-Met/HGFR

Research Areas:  

Cancer

CE-355621 is a humanized anti-c-Met IgG1 monoclonal antibody. CE-355621 can effectively bind with human c-Met (KD = 200 pM, IC50 = 466 pM) in A549 cells and cyno c-Met (KD = 610 pM) in cynomolgus kidney cells. CE-355621 inhibits the c-Met signaling pathway by blocking HGF binding. CE-355621 significantly inhibits the growth of tumors dependent on the c-Met/HGF pathway. CE-355621 can be used for research on cancer such as glioblastoma and gastric cancer .
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