1 Result for "

CJM-112

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "CJM-112" in MCE Product Catalog:

Cat. No.: HY-P991261

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

CJM112 is a fully human IgG1/κ monoclonal antibody inhibitor targeting IL-17A, which binds to IL-17A and the IL-17AF heterodimer with high affinity, with KD values of 5.7 pM and <11 pM, respectively. CJM-112 exerts anti-inflammatory effects by neutralizing IL-17A, and reduces the Psoriasis Area and Severity Index in a time- and dose-dependent manner. CJM-112 also exhibits anti-inflammatory activity and improves disease severity in studies of hidradenitis suppurativa. CJM-112 shows favorable biosafety and tolerability. CJM-112 can be used in studies related to psoriasis and hidradenitis suppurativa .
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