1 Result for "

CM 118

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "CM 118" in MCE Product Catalog:

Cat. No.: HY-165284
CAS No.: 1370652-56-4
Research Areas:  

Cancer

CM-118 is a potent and selective c-Met and ALK inhibitor. CM-118 inhibits the HGF-induced c-Met phosphorylation. CM-118 inhibits phosphorylation of ALK, EML4-ALKv1, ALK F1174L, and EMl4-ALKv1 L1196M, with respective IC50 values 0.92, 1.25, 1.9, and 3.5 μM. CM-118 exhibits anticancer activity against cancers dependent on the c-Met or ALK oncogenic pathways .
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