2 Results for "

Cbl-b-IN-2

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Cbl-b-IN-2" in MCE Product Catalog:

Cat. No.: HY-141431
CAS No.: 2503325-21-9
Target:  

E1/E2/E3 Enzyme

Research Areas:  

Inflammation/Immunology Cancer

Cbl-b-IN-2 (Example 8) is an orally bioavailable compound, can inhibit the E3 enzyme Casitas B-lineage lymphoma proto-oncogene-b (Cbl-b) in the ubiquitin proteasome pathway. Cbl-b-IN-2 can be used to modulate the immune system and diseases amenable to immune system modulation. Cbl-b-IN-2 (Example 8) also may be administered to an individual with cancer, either alone or as part of a combination, with one or more of an immune checkpoint inhibitor, an anti-neoplastic agent, and radiation agent .
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Cat. No.: HY-P11481
Research Areas:  

Others

FITC-Acp-RpYTPEP-NH2 is a potent fluorescent tracer. FITC-Acp-RpYTPEP-NH2 shows a binding affinity (Kd = 0.07 μM) for the Cbl-b SH2 domain. Fluorescence polarization assay based on FITC-Acp-RpYTPEP-NH2 can be for evaluating Cbl-b SH2 domain inhibitors .
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