1 Result for "

ClpP agonist1

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "ClpP agonist1" in MCE Product Catalog:

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Cat. No.: HY-182033
CAS No.: 2761081-10-9
Target:  

Bacterial ClpP

Research Areas:  

Infection

ClpP agonist 1 is a Staphylococcus aureus ClpP (SaClpP) agonist with an EC50 of 1.44 μM, Kd values of 2.95 μM (isothermal titration calorimetry) and 18 μM (bio-layer interferometry), and a low drug resistance frequency. ClpP agonist 1 reduces bacterial load, shrinks infected area and improves histopathological outcomes in a mouse skin infection model. ClpP agonist 1 can be used for the research of Methicillin (HY-121544)-resistant Staphylococcus aureus (MRSA) skin infections .
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