1 Result for "

DBM-819

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "DBM-819" in MCE Product Catalog:

Cat. No.: HY-126751
CAS No.: 331686-58-9
Target:  

Na+/K+ ATPase

Research Areas:  

Metabolic Disease

DBM-819 is a reversible inhibitor of H⁺/K⁺-ATPase (H +/K +-ATPase), with an IC50 value of 5 μM. DBM-819 can reversibly block gastric acid secretion by inhibiting the proton pump in the gastric mucosa. It shows significant protective effects against duodenal ulcers induced by Cysteamine (HY-77591), gastric ulcers induced by Indomethacin (HY-14397), and gastric ulcers induced by Aspirin (HY-14654), with EC50 values of 6, 3.1, and 4 mg/kg respectively. DBM-819 can be used in ulcer prevention research .
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