2 Results for "

DNIB0600A

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "DNIB0600A" in MCE Product Catalog:

Cat. No.: HY-P99705
CAS No.: 1401812-88-1
Synonyms: RG-7599; DNIB-0600A; NaPi2b-ADC
Research Areas:  

Cancer

Lifastuzumab vedotin (RG-7599; DNIB0600A) is an antibody-drug conjugate (ADC) that comprises a humanized IgG1 anti-NaPi2b monoclonal antibody (MNIB2126A) and a potent antimitotic agent, monomethyl auristatin E (MMAE), which inhibits cell division by blocking the polymerization of tubulin. Lifastuzumab vedotin has the potential for non-small cell lung cancer (NSCLC) and platinum-resistant ovarian cancer (PROC) research .
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Cat. No.: HY-P99970
CAS No.: 1615697-16-9

Research Areas:  

Cancer

Lifastuzumab is a humanized anti-NaPi2b IgG1 monoclonal antibody. Lifastuzumab can be coupled with monomethyl auristatin E (MMAE) (HY-15162) through ADC Linker to form an antibody-drug conjugate (ADC) Lifastuzumab vedotin (HY-P99705) with anticancer activity. Lifastuzumab vedotin can be studied in research for non-small cell lung cancer and ovarian cancer. Recommend Isotype Control: Human IgG1 kappa, Isotype Control (HY-P99001) .
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