3 Results for "

Dendroaspis polylepis

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "Dendroaspis polylepis" in MCE Product Catalog:

Cat. No.: HY-P3269
CAS No.: 178805-91-9
Target:  

Calcium Channel

Research Areas:  

Cardiovascular Disease

Calciseptine is a natural polypeptide toxin found in the venom of the black mamba snake (Dendroaspis p. polylepis). Calciseptine is a highly effective and selective blocker of the L-type channel of the Cav1.2 subtype, with an IC50 value of 92 nM. Calciseptine has no effect on Cav3.1, Cav2.2, Cav2.1, Cav1.1, voltage-sensitive sodium channels and potassium channels. Calciseptine exhibits negative inotropic and negative relaxant effects on mice, and does not affect heart rate or the action potential of sinoatrial node pacemaker cells. Calciseptine can be used for research on cardiovascular diseases[1].
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Cat. No.: HY-P5796
Target:  

Calcium Channel

Research Areas:  

Neurological Disease

FS-2 is a potent and specific L-type CaV channel inhibitor. FS-2 inhibits high K + or glucose induced L-type Ca 2+ influx in RIN beta cells .
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Cat. No.: HY-P705701
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Toxin MIT1; MIT 1; Black mamba intestinal toxin 1; Black mamba venom protein A
Species:  
Source:  
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