1 Result for "

EZM8266

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "EZM8266" in MCE Product Catalog:

Cat. No.: HY-183058
CAS No.: 2140164-84-5
Research Areas:  

Cancer

EZM8266 is an orally active and selective G9a (EHMT2) histone methyltransferase inhibitor with a human EHMT2 IC50 of 1 pM. EZM8266 reduces repressive H3K9me2 marks at immune-stimulatory gene and endogenous retroviral element promoters. EZM8266 reduces colony formation, migration, and invasion of cancer cells. EZM8266 enhances IFN-γ response, increases MHC class I expression, and enhances CXCL10-mediated T cell recruitment in cancer cells. EZM8266 can be used for the research of hepatocellular carcinoma .
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