1 Result for "

F44-A13

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "F44-A13" in MCE Product Catalog:

Cat. No.: HY-163436
CAS No.: 1338190-14-9
Research Areas:  

Metabolic Disease

F44-A13 is an orally active and highly selective farnesoid X receptor (FXR) antagonist with an IC50 value of 1.1 μM. F44-A13 can optimize cholesterol metabolism and reduce its activity by inducing CYP7A1 expression. F44-A13 reduces levels of cholesterol, triglycerides, and low-density lipoprotein cholesterol (LDL-C) in mouse models. F44-A13 can be used in the study of metabolic diseases associated with lipid disorders .
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