1 Result for "

FXR agonist13

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "FXR agonist13" in MCE Product Catalog:

  • Targets Recommended:
Cat. No.: HY-178959
Target:  

FXR

FXR agonist 13 is a selective, orally active, potent FXR agonist (EC50 = 0.097 μM) and has favorable hepatic microsomal metabolic stability. FXR agonist 13 exhibits moderate affinity for FXR-LBD upon direct binding (KD = 14.74 μM). FXR agonist 13 displays good selectivity against related nuclear receptors, including LXRα/β, PPARα/γ/δ, PXR, and TGR5. FXR agonist 13 can be used for the study of metabolic-associated steatohepatitis (MASH) .
loading...
    loading...