4 Results for "

GppNHp

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "GppNHp" in MCE Product Catalog:

Guanylyl imidodiphosphate lithium
Guanylyl imidodiphosphate lithium
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Cat. No.: HY-137167
CAS No.: 64564-03-0
Pureté:  ≥98.0%
Synonyms: Gpp(NH)p lithium
Target:  

Adenylate Cyclase

Domaines de recherche:  

Metabolic Disease

Guanylyl imidodiphosphate lithium (Gpp (NH) p lithium) is a non-hydrolyzable GTP analog. Guanylyl imidodiphosphate lithium increases adenylate cyclase activity. Guanylyl imidodiphosphate lithium binds to and irreversibly activates G proteins .
(R)-G12Di-7
(R)-G12Di-7
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Cat. No.: HY-158008
CAS No.: 2946593-60-6
Target:  

Ras

Domaines de recherche:  

Cancer

(R)-G12Di-7 is a covalent ligand for KRAS-G12D, which selectively labels K-Ras-G12D·GDP and K-Ras-G12D·GppNHp. (R)-G12Di-7 exhibits inhibitory activity against G12D mutated cancer cells .
MANT-GppNHp
MANT-GppNHp
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Cat. No.: HY-137744
CAS No.: 148821-01-6
Target:  

Adenylate Cyclase Nucleoside Antimetabolite/Analog

Domaines de recherche:  

Infection

MANT-GppNHp is a competitive adenyl cyclase (AC) inhibitor. MANT-GppNHp is a fluorescently labeled GTP (HY-113225) analogue. MANT-GppNHp interacts with the hydrophobic pocket near the AC catalytic site through its MANT group, thereby directly blocking the binding of the substrate ATP. MANT-GppNHp can be used to study diseases related to the increased activity of AC (such as cholera) .
Agaridoxin
Agaridoxin
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Cat. No.: HY-121578
CAS No.: 58298-77-4
Synonyms: GDHB
Target:  

Adrenergic Receptor

Domaines de recherche:  

Neurological Disease

Agaridoxin (GDHB) is a blocker of catecholamine and adrenergic alpha-type receptors isolated from mushrooms. Agaridoxin activates adenylyl cyclase in rat hypothalamic membrane granules in the presence of guanosyl imide diphosphate (Gpp(NH)p) .
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