2946593-60-6
2946593-60-6
Chemical Structure
(R)-G12Di-7
- CAS No.: 2946593-60-6
- Formula:C39H37F3N6O5
- Molecular Weight:726.74
InChIKey: CRALQCNGTOLNEF-SHEZVGAFSA-N
SMILES: C#CC1=C(C=CC2=CC(O)=CC(C3=C(C4=C(C(N5CC6CCC(N6C([C@@H]7OC(C7(C)C)=O)=O)C5)=NC(OC[C@@]89CCCN8C[C@@H](C9)F)=N4)C=N3)F)=C21)F
Biological Activity: (R)-G12Di-7 is a covalent ligand for KRAS-G12D, which selectively labels K-Ras-G12D·GDP and K-Ras-G12D·GppNHp. (R)-G12Di-7 exhibits inhibitory activity against G12D mutated cancer cells[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(R)-G12Di-7 | 98.42% | (R)-G12Di-7 is a covalent ligand for KRAS-G12D, which selectively labels K-Ras-G12D·GDP and K-Ras-G12D·GppNHp. (R)-G12Di-7 exhibits inhibitory activity against G12D mutated cancer cells. | ||||||||||||||||||||
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References
Keywords
