4 Results for "

H2-K1

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "H2-K1" in MCE Product Catalog:

Cat. No.: HY-181877
Target:  

HDAC Adenosine Receptor

Research Areas:  

Cancer

IHCH-3185 is an orally active class I HDAC inhibitor (HDAC1 IC50 =102.9 nM) and A2AR antagonist (A2AR Ki =7.6 nM). IHCH-3185 reverses immune gene silencing by inducing histone acetylation and blocks the adenosine signaling pathway to relieve T-cell suppression. IHCH-3185 exhibits antiproliferative activity, induces cell cycle arrest, and significantly improves the tumor microenvironment. IHCH-3185 reduces the proportion of regulatory T cells, increases the CD8 +/Treg ratio, and upregulates the expression of key factors such as H2-K1, Cxcl9 and Cxcl10. IHCH-3185 shows significant antitumor potential in CT26 and MC38 mouse tumor models and is suitable for related cancer research .
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Cat. No.: HY-P705400
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: H-2 class I histocompatibility antigen, K-B alpha chain; H-2K(B); H2-K1; H2-K; B2M; Beta 2-Microglobulin; Beta-2-Microglobulin; Beta-2-Microglobin; Beta Chain Of MHC Class I Molecules; AMYLD6; Beta 2-Microglobulin Protein; MHC1D4; Human Nkt Tcr Alpha Chai
Species:  
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Cat. No.: HY-P703712
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: H-2 class I histocompatibility antigen, K-B alpha chain; H-2K(B); H2-K1; H2-K; B2M; Beta 2-Microglobulin; Beta-2-Microglobulin; Beta-2-Microglobin; Beta Chain Of MHC Class I Molecules; AMYLD6; Beta 2-Microglobulin Protein; MHC1D4; Human Nkt Tcr Alpha Chai
Species:  
Source:  
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Cat. No.: HY-P705401
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: H-2 class I histocompatibility antigen, K-B alpha chain; H-2K(B); H2-K1; H2-K; B2M; Beta 2-Microglobulin; Beta-2-Microglobulin; Beta-2-Microglobin; Beta Chain Of MHC Class I Molecules; AMYLD6; Beta 2-Microglobulin Protein; MHC1D4; Human Nkt Tcr Alpha Chai
Species:  
Source:  
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