1 Result for "

HDAC-IN-76

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "HDAC-IN-76" in MCE Product Catalog:

Cat. No.: HY-161984
Target:  

HDAC

Research Areas:  

Infection Others

HDAC-IN-76 (compound 6i) is a histone deacetylase (HDAC) inhibitor. HDAC-IN-76 IC50 values of 30 nM and 98 nM for Pf3D7 (chloroquine (HY-17589A) drug-susceptible strain) and PfDd2 (chloroquine (HY-17589A) drug-resistant strain), has a highly potent antimalarial activity against asexual blood-stage Plasmodium, respectively, and exhibits selective inhibition against parasites, with IC50 values of 7 nM and 9 nM for human HDAC1 and HDAC6, respectively, while inhibiting PfHDAC1 .
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