1 Result for "

HQY1428

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "HQY1428" in MCE Product Catalog:

Cat. No.: HY-172970
CAS No.: 3093763-71-1
Research Areas:  

Cancer

HQY1428 is an orally active CDK12 inhibitor. HQY1428 inhibits DNA replication, causes G2/M arrest in SKOV3 cells, induces DNA double-strand breaks and apoptosis. HQY1428 has anti-tumor activity in the SKOV3 xenograft mouse model. HQY1428 combined with the HER2 inhibitor Lapatinib (HY-50898) in the NCI-N87 xenograft mouse model produces a synergistic therapeutic effect .
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