1 Result for "

HSD17B isoforms

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "HSD17B isoforms" in MCE Product Catalog:

Cat. No.: HY-183309
Target:  

FXR 17β-HSD

Research Areas:  

Inflammation/Immunology

FXR/HSD17B13-modulator-2 is a dual FXR activator and HSD17B13 inhibitor with human FXR EC50 of 128 nM, human HSD17B13 IC50 of 0.18 μM, high selectivity over related nuclear receptors and HSD17B isoforms, and oral effectiveness.FXR/HSD17B13-modulator-2 alleviates fatty liver, regulates lipid metabolism, reduces inflammation, and attenuates hepatic fibrosis.FXR/HSD17B13-modulator-2 is the first non-carboxylic acid dual FXR/HSD17B13 modulator.FXR/HSD17B13-modulator-2 can be used for the research of metabolic dysfunction-associated steatohepatitis .
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