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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
103 Results for "
Homeobox
" in MedChemExpress (MCE) Product Catalog:
Products (103)
103 Results for "Homeobox" in MCE Product Catalog:
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MI-389 is a potent menin-MLL interaction inhibitor (IC50=25 nM). MI-389 upregulates myeloid differentiation-related genes that are lowly expressed in primitive hematopoietic progenitor cells, thereby inducing myeloid differentiation phenotypic changes in MLL-rearranged leukemia cells. MI-389 competitively blocks the MG-H1-RAGE interaction to interfere with the AGEs-RAGE pathway, thus alleviating AGEs-induced HUVEC injury . MI-389 can be used in studies related to MLL-rearranged acute leukemia .
Cat. No.: HY-122623A
Purity: 99.43%
DB818 dihydrochloride is the dihydrochloride salt form of DB818 (HY-122623). DB818 dihydrochloride is an inhibitor for Homeobox A9 (HOXA9). DB818 dihydrochloride reduces the formation of HOXA9-DNA complexes, inhibits the growth and induces apoptosis in AML cell lines OCI/AML3, MV4-11, and THP-1 .
Cat. No.: HY-RS07546
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LBX1 Human Pre-designed siRNA Set A contains three designed siRNAs for LBX1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-174574
Human NANOG mRNA encodes the human Nanog homeobox (NANOG) protein, a DNA binding homeobox transcription factor that involved in embryonic stem (ES) cell proliferation, renewal, and pluripotency. NANOG can block ES cell differentiation and autorepress its own expression in differentiating cells.
Cat. No.: HY-174544
Human POU class 5 homeobox 1 (POU5F1) mRNA encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis.
Cat. No.: HY-174594
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Human ISL1 mRNA encodes the human ISL LIM homeobox 1 (ISL1) protein, a member of the LIM/homeodomain family of transcription factors. ISL1 is central to the development of pancreatic cell lineages and may also be required for motor neuron generation.
Cat. No.: HY-174669
Human HNF1A mRNA encodes the human HNF1 homeobox A (HNF1A) protein, a transcription factor that required for the expression of several liver-specific genes. HNF1A functions as a homodimer and binds to the inverted palindrome 5''-GTTAATNATTAAC-3''.
Cat. No.: HY-174668
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Human HNF1B mRNA encodes the human HNF1 homeobox B (HNF1B) protein, a member of the homeodomain-containing superfamily of transcription factors. HNF1B has been shown to function in nephron development, and regulates development of the embryonic pancreas.
Cat. No.: HY-174591
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Human LHX3 mRNA encodes the human LIM homeobox 3 (LHX3) protein, a member of a large proteins family which carry the LIM domain, a unique cysteine-rich zinc-binding domain. LHX3 is a transcription factor that is required for pituitary development and motor neuron specification.
Cat. No.: HY-174545
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Human POU3F2 mRNA encodes the human POU class 3 homeobox 2 (POU3F2) protein, a member of the POU-III class of neural transcription factors. POU3F2 is involved in neuronal differentiation and enhances the activation of corticotropin-releasing hormone regulated genes.
Cat. No.: HY-174589
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Human LMX1A mRNA encodes the human LIM homeobox transcription factor 1 alpha (LMX1A) protein, a homeodomain and LIM-domain containing protein. LMX1A is a transcription factor that acts as a positive regulator of insulin gene transcription. It also plays a role in the development of dopamine producing neurons during embryogenesis.
Cat. No.: HY-174547
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Human PDX1 mRNA encodes the human pancreatic and duodenal homeobox 1 (PDX1) protein, a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. PDX1 may be involved in the early development of the pancreas. It also plays a major role in glucose-dependent regulation of insulin gene expression.
Cat. No.: HY-171290
CAS No.: 2567490-30-4
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Casein kinase 1δ-IN-31 (Compound 16) is the inhibitor for casein kinase (CK) that inhibits CK1α, CK1δ, and p38α with IC50s of 196, 17, and 18 nM, respectively. Casein kinase 1δ-IN-31 inhibits Double Homeobox 4 (DUX4) with IC50 of 1200 nM .
Cat. No.: HY-174579
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Human MNX1 mRNA encodes the human motor neuron and pancreas homeobox 1 (MNX1) protein, a putative transcription factor involved in pancreas development and function.
Cat. No.: HY-P810441
Synonyms: Homeobox prospero like protein, Homeobox prospero like protein PROX1, Homeobox prospero-like protein PROX1, Prospero Homeobox 1, Prospero Homeobox protein 1, Prospero related Homeobox 1, prospero-related Homeobox gene 1, PROX 1, PROX-1, PROX1
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
