1 Result for "

IASO782

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "IASO782" in MCE Product Catalog:

Cat. No.: HY-P991898
Synonyms: RD126

Target:  

CD19

Research Areas:  

Inflammation/Immunology

IASO-782 (RD126) is a fully human monoclonal antibody targeting human CD19. The Fc segment of IASO-782 is mutated to enhance antibody-dependent cell-mediated cytotoxicity (ADCC) while maintaining the integrity of other Fc segment functions, such as ADCP. IASO-782 effectively eliminates CD19+ B cells, plasmablasts, and some plasma cells, thereby reducing or completely eliminating autoreactive antibodies produced by these cells. IASO-782 can be used for the study of immune thrombocytopenic purpura (ITP), warm autoimmune hemolytic anemia (wAIHA) and systemic lupus erythematosus (SLE).
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