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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
IL-33/ST2
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "IL-33/ST2" in MCE Product Catalog:
3
3 Cited Publications
Referencia número: HY-P99444
No. CAS: 2173054-79-8
Synonyms: MSTT 1041A; RG 6149
Target:
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Referencia número: HY-168532
No. CAS: 3099811-61-4
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Áreas de investigación:
ST2-IN-1 is a ST2 inhibitor. ST2-IN-1 blocks the binding interaction between ST2 and IL-33, thereby attenuating the downstream ST2/IL-33 signaling pathway. ST2-IN-1 reduces IL-1β release from mast cells and alleviates ST2 upregulation in cells. ST2-IN-1 can be used for research on inflammatory and immune-related diseases .
Referencia número: HY-P99729
No. CAS: 2222865-46-3
Synonyms: GSK 3772847; CNTO-7160
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Referencia número: HY-P991633
Target:
Áreas de investigación:
Referencia número: HY-W060417
No. CAS: 1019158-02-1
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Áreas de investigación:
iST2-1 is an Stimulation-2 (ST2) inhibitor with an IC50 value of 46.65 μM, blocks interaction between ST2 and IL-33, inhibits downstream signaling. iST2-1 functions as an immunomodulator, reduces proliferation of CD4 + and CD8 + T cells, increases regulatory T cell populations, reduces IFN-γ +CD4 + T cell populations, increases Foxp3 +CD4 + regulatory T cell populations in the gastrointestinal tract. iST2-1 reduces plasma soluble ST2 and IFN-γ levels, reduces graft-versus-host disease scores, improves survival in graft-versus-host disease animal models, preserves graft-versus-tumor effect. iST2-1 can be used for the research of graft-versus-host disease [2].
Referencia número: HY-174607
Target:
Áreas de investigación:
Human IL33 mRNA encodes the human interleukin 33 (IL33) protein, a cytokine that binds to the IL1RL1/ST2 receptor. IL33 is involved in the maturation of Th2 cells and the activation of mast cells, basophils, eosinophils and natural killer cells.
Referencia número: HY-P992440
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Referencia número: HY-P87275
Synonyms: DER-4 antibody; DER4 antibody; FIT 1 antibody; Growth STimulation expressed antibody; homolog of mouse growth STimulation-expressed antibody; IL1rl1 antibody; IL33R antibody; ILRL1_HUMAN antibody; Interleukin 1 receptor like 1 antibody; interleukin 1 receptor related protein antibody
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
