1 Result for "

INCB086550

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "INCB086550" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-134884
CAS No.: 2230911-59-6
Purity:  99.80%
Synonyms: PD-1/PD-L1-IN-8
Target:  

PD-1/PD-L1

Research Areas:  

Cancer

INCB086550 is a potent, oral, small-molecule PD-L1 inhibitor with IC50s value of 3.1, 4.9 and 1.9 nM for human, cynomolgus, and rat, respectively. INCB086550 promotes the dimerization of cell-surface PD-L1 and induces PD-L1 entry into Golgi vesicles then traffick to the nucleus. INCB086550 can be used for multiple cancers research .
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