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IUB288

" in MedChemExpress (MCE) Product Catalog:

By Targets:	FGFR (1) GCGR (1) GLP Receptor (1) HMG-CoA Reductase (HMGCR) (1)
By Research Areas:	Metabolic Disease (1)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

*IUB288*	GCGR GLP Receptor FGFR HMG-CoA Reductase (HMGCR)	Metabolic Disease
IUB288 is a stable and long-acting glucagon-modified peptide, as well as a highly selective Glucagon Receptor agonist. IUB288 stimulates the production of cAMP, increases the expression levels of FGF21 in plasma and liver, regulates bile acid metabolism, and inhibits the expression of hepatic HMGCR. IUB288 improves hypercholesterolemia, enhances insulin sensitivity, increases core body temperature, boosts energy expenditure, suppresses food intake, and can also induce hyperglycemia and glucose intolerance. IUB288 is applicable to the research of diet-induced obesity, type 2 diabetes, and obesity-related glucose intolerance .

Cat. No.	Product Name	Target	Research Area

*IUB288*	GCGR GLP Receptor FGFR HMG-CoA Reductase (HMGCR)	Metabolic Disease
IUB288 is a stable and long-acting glucagon-modified peptide, as well as a highly selective Glucagon Receptor agonist. IUB288 stimulates the production of cAMP, increases the expression levels of FGF21 in plasma and liver, regulates bile acid metabolism, and inhibits the expression of hepatic HMGCR. IUB288 improves hypercholesterolemia, enhances insulin sensitivity, increases core body temperature, boosts energy expenditure, suppresses food intake, and can also induce hyperglycemia and glucose intolerance. IUB288 is applicable to the research of diet-induced obesity, type 2 diabetes, and obesity-related glucose intolerance .

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