1 Result for "

KFP-H008

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "KFP-H008" in MCE Product Catalog:

Cat. No.: HY-180348
CAS No.: 1876453-55-2
Target:  

p38 MAPK ATP Synthase

Research Areas:  

Inflammation/Immunology

KFP-H008 is an orally active potassium-competitive acid blocker. KFP-H008 inhibits gastric acid secretion through blocking H +-K +-ATPase. KFP-H008 reduces ethanol-induced gastric ulcer index and malonaldehyde as well as proinflammatory cytokine expression in vivo. KFP-H008 downregulates p-p38 MAPK and p65 NF-κB expression. KFP-H008 blocks histamine-stimulated acid secretion in rat and dog models. KFP-H008 can be studied in research on acid-related disease, such as ethanol-induced gastric ulcer and gastric epithelial cell damage .
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