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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1 Result for "
KMG732
" in MedChemExpress (MCE) Product Catalog:
Products (1)
1 Results for "KMG732" in MCE Product Catalog:
Cat. No.: HY-184580
Research Areas:
KMG-732 is a dual-target inhibitor that targets GAK and β-tubulin, with Kd values of 12.0 nM and 19.3 μM, respectively. KMG-732 exhibits broad-spectrum antiproliferative activity in various human cancer cell lines and directly binds to purified tubulin in vitro. KMG-732 reduces the phosphorylation level of AP2M1, induces G2/M phase cell cycle arrest, disrupts the microtubule network, and inhibits cancer cell migration and invasion. KMG-732 shows significant antitumor activity in organoid and in vivo xenograft models. KMG-732 can be used for cancer research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
