2 Results for "

L006235

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "L006235" in MCE Product Catalog:

Cat. No.: HY-103352
CAS No.: 294623-49-7
Purity:  99.96%
Synonyms: L-235
Target:  

Cathepsin

Research Areas:  

Metabolic Disease

L-006235 (L-235) is a potent, selective, reversible and orally active inhibitor of cathepsin K, with an IC50 of 5 nM in bone resorption assay. L-006235 shows selectivity for cathepsin K (Ki=0.2 nM) over cathepsin B, cathepsin L, and cathepsin S (Ki=1, 6, and 47 μM, respectively). L-006235 can reduce collagen degradation and prevent bone loss .
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Cat. No.: HY-103352R
CAS No.: 294623-49-7
Synonyms: L-235 (Standard)
Research Areas:  

Metabolic Disease

L-006235 (Standard) is the analytical standard of L-006235. This product is intended for research and analytical applications. L-006235 (L-235) is a potent, selective, reversible and orally active inhibitor of cathepsin K, with an IC50 of 5 nM in bone resorption assay. L-006235 shows selectivity for cathepsin K (Ki=0.2 nM) over cathepsin B, cathepsin L, and cathepsin S (Ki=1, 6, and 47 μM, respectively). L-006235 can reduce collagen degradation and prevent bone loss .
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