1 Result for "

LC-TEAD01

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "LC-TEAD01" in MCE Product Catalog:

Cat. No.: HY-183728
Target:  

YAP

Research Areas:  

Cancer

LC-TEAD01 is a potent covalent transcription enhancer-associated domain (TEAD) inhibitor with an IC50 of 116 nM and a Ki of 0.132 μM. LC-TEAD01 disrupts the TEAD-YAP interaction and inhibits TEAD-dependent transcriptional activity. LC-TEAD01 suppresses the proliferation of NF2-deficient cancer cells. LC-TEAD01 inhibits tumor growth in NF2-deficient xenograft models. LC-TEAD01 can be used in studies related to NF2-deficient malignant pleural mesothelioma .
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