1 Result for "

Lifitegrast-d6

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "Lifitegrast-d6" in MCE Product Catalog:

Cat. No.: HY-19344S1
CAS No.: 2249814-79-5
Synonyms: SAR 1118-d6; SHP-606-d6
Lifitegrast-d6 (SAR 1118-d6) is deuterium labeled Lifitegrast. Lifitegrast (SAR 1118) is a potent integrin antagonist. Lifitegrast blocks the binding of intercellular adhesion molecule 1 (ICAM-1) to lymphocyte function-associated antigen 1 (LFA-1), interrupting the T cell-mediated inflammatory cycle. Lifitegrast inhibits Jurkat T cell attachment to ICAM-1 with an IC50 of 2.98 nM. Lifitegrast can be used for researching dry eye disease .
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