1 Result for "

ML218 (Standard)

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ML218 (Standard)" in MCE Product Catalog:

Cat. No.: HY-103309R
CAS No.: 1346233-68-8
Research Areas:  

Neurological Disease

ML218 (Standard) is the analytical standard of ML218 (HY-103309). This product is intended for research and analytical applications. ML218 is a potent, selective and orally active T-type Ca2+ channels (Cav3.1, Cav3.2, Cav3.3) inhibitor with IC50s of 310 nM and 270 nM for Cav3.2 and Cav3.3, respectively. ML218 inhibits the burst activity in subthalamic nucleus (STN) neurons. ML218 has no significant inhibition of L- or N-type calcium channels, KATP or hERG potassium channels. ML218 can penetrate the blood-brain barrier .
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