1 Result for "

ML221 analogs

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ML221 analogs" in MCE Product Catalog:

Cat. No.: HY-175818
Target:  

Apelin Receptor (APJ)

Research Areas:  

Cancer

APJ antagonist-1 is an apelin receptor (APJ) antagonist. APJ antagonist-1 shows strong β-arrestin inhibition with an IC50 of 3.1 μM. APJ antagonist-1 selectively inhibits APJ-overexpressing cancer cells and suppresses apelin-induced endothelial cell migration. APJ antagonist-1exhibits high metabolic stability. APJ antagonist-1 can used for the studies of ovarian cancer and tumor angiogenesis .
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