1 Result for "

MS105

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "MS105" in MCE Product Catalog:

Art. -Nr.: HY-171830
CAS. Nr.: 2408339-39-7
Synonyms: YX39-105
Forschungsgebiete:  

Cancer

MS105 (YX39-105) is an orally active and selective protein tyrosine kinase 6 (PTK6) (BRK) PROTAC degrader. MS105 recruits VHL E3 ligase via a VHL ligand moiety, promotes PTK6 ubiquitination and proteasomal degradation, inhibits the proliferation and migration of breast cancer cells, and induces apoptosis. MS105 shows potential for use in breast cancer research .
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