1 Result for "

MS1129

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "MS1129" in MCE Product Catalog:

Cat. No.: HY-181955
MS1129 is a DNMT degrader that induces proteasomal degradation of DNMT1, DNMT3A and DNMT3B proteins. MS1129 upregulates TRAIL, DR4 and DR5 proteins, downregulates the decoy receptor DcR2, and activates TRAIL-dependent apoptosis via the HIF-1/2 and Caspase-10 pathways. MS1129 is applicable to the research of VHL-deficient clear cell renal cell carcinoma .
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