1 Result for "

Mouse Tnf ASO

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Mouse Tnf ASO" in MCE Product Catalog:

Cat. No.: HY-188018
Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

Mouse Tnf ASO is an antisense oligonucleotide (ASO) that targets the expression of mouse TNF-α. Mouse Tnf ASO reduces the tissue levels of various pro-inflammatory cytokines, Th1 cytokines and Th17 cytokines. Mouse Tnf ASO improves the clinical and histopathological severity of experimental colitis, including alleviating weight loss, diarrhea and intestinal protein loss. Mouse Tnf ASO can be delivered to activated colonic macrophages in mice via galactosylated low-molecular-weight chitosan nanocomplexes, with higher delivery efficiency compared to naked ASO. Mouse Tnf ASO can be used in the research of Crohn's disease .
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